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The alcoholic extract of R.
cordifolia has been
shown to significantly inhibit potato lipoxygenase[1]
Rubia cordifolia elevated expression of γ-glutamylcysteine
ligase in rat hippocampal slices[2]
mollugin isolated from Rubia cordifolia caused inhibition of CYP1A2 in human liver microsomes.[3]
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REFERENCES: |
1. |
Tripathi YB et al, Rubia cordifolia inhibits potatolipoxygenases. Indian Journal of Experimental Biology. 1995; 33(2): 109-112.
http://eurekamag.com/research/002/690/002690269.php |
2. |
Rawal A, Muddeshwar M, Biswas S, Effect of Rubia cordifolia, Fagonia cretica linn, and Tinospora
cordifolia on free radical generation and lipid peroxidation
during oxygenglucose
deprivation in rat hippocampal slices. Biochemical and Biophysical Research
Communications 2004; 324(2):588–596.
http://dx.doi.org/10.1016/j.bbrc.2004.09.094 |
3. |
Kim H et al, Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes. Food Chem Toxicol. 2013;51:33-7.
http://dx.doi.org/10.1016/j.fct.2012.09.013 |