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Zingiber officinale

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GENERAL FEATURES

Name: Zingiber officinale
Synonyms/Scientific names: Zingiber officinale Roscoe[1],[2]
Amomum zingiber L.[1],[2]
Synonyms/common names :
Ginger[1]
Trade name:
Description: Family : Zingiberaceae[1-lim]
Extract used: Rhizome:
hydroalcoholic extract of rhizome has been used for radioprotection study[3],[4]
Phyto-constituents
(active):
Rhizome:
gingerol related compounds and diarylheptanoids[5]
beta-sitosterol palmitate, isovanillin, glycol monopalmitate, hexacosanoic acid 2,3-dihydroxypropyl ester, maleimide-5-oxime, p-hydroxybenzaldehyde, adenine, 6-gingerol, 6-shogaol, and 1-(omega-ferulyloxyceratyl) glycerols[6]
Actions
& Indications:
Pharmcological Action-
Antidiabetic and hypolipidaemic properties in rats[7]
hepatoprotective in rats[8],[9],[10]
Analgesic, antiinflammatory and hypoglycaemic effects in mice and rats[11]
cholesterol lowering, antithrombotic and anti-inflammatory agent in rats[12]
anticonvulsant, anxiolytic and antiemetic activity in animals[13]
gastroprotective in rats[14]
Therapeutic indications:
Preclinical study-
It is shown to offer relief in cases of rheumatism and musculoskeletal disorders[15]
Notes:
REFERENCES
1. Zingiber officinale ; In :Edible Medicinal and Non-Medicinal Plants: Volume 12 Modified Stems, Roots, Bulbs, by Lim TK, Springer, 2016, Page no. 469.
https://books.google.com.sg/books?id=d42RCwAAQBAJ&pg=PA469
2. Ginger: Section 1: Herb-drug Interaction ; In : Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies by Stargrove MB, Treasure J, McKee DL. Elsevier, 2008, Page no. 62.
https://books.google.com.sg/books?id=49kLK--eumEC&pg=PA62
3. Jagetia GC et al, Influence of Ginger rhizome (Zingiber officinale Rosc) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat. Res. 2003; 160(5):584-592.
http://dx.doi.org/10.1667/RR3057
4. Jagetia GC, Baliga M, Venkatesh P, Ginger (Zingiber officinale Rosc.), a dietary supplement, protects mice against radiation- induced lethality: mechanism of action. Cancer Biotherapy & Radiopharmaceuticals. 2004;19(4):422-435.
http://dx.doi.org/10.1089/cbr.2004.19.422
5. Masuda Y et al, Antioxidant properties of gingerol related compounds from ginger. Biofactors. 2004;21(14): 293-6.
http://dx.doi.org/10.1002/biof.552210157
6. Bao L et al, Chemical constituents of rhizomes of Zingiber officinale. Zhongguo Zhong Yao Za Zhi. 2010;35(5):598-601.
http://www.ncbi.nlm.nih.gov/pubmed/20506819
7. Al-Amin ZM et al, Antidiabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocininduced diabetic rats. Br J Nutr. 2006;96(4):660-6.
http://dx.doi.org/10.1079/BJN20061849
8. Bardi DA et al, In vivo evaluation of ethanolic extract of Zingiber officinale rhizomes for its protective effect against liver cirrhosis. BioMed Research International Volume 2013, Article ID 918460, 10 pages.
http://dx.doi.org/10.1155/2013/918460
9. Dalia FA, Repair of Carbon Tetrachloride-induced rat liver injury by Ginger extract (Zingiber officinale). Egypt. J. Exp. Biol. (Zoo.). 2007; 3(0): 211-217.
http://www.scopemed.org/?mno=188082
10. Yemitan OK, Izegbu MC, Protective effects of Zingiber officinale (Zingiberaceae) against carbon tetrachloride and acetaminopheninduced hepatotoxicity in rats. Phytother Res. 2006;20(11):997-1002.
http://dx.doi.org/10.1002/ptr.1957
11. Ojewole JA, Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother Res. 2006;20(9):764-72.
http://dx.doi.org/10.1002/ptr.1952
12. Thompson M et al, The use of ginger (Zingiber officinale Rosc.) as a potential antiinflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids. 2002 ;67(6):475-8.
http://dx.doi.org/10.1054/plef.2002.0441
13. Vishwakarma SL et al, Anxiolytic and antiemetic activity of Zingiber officinale. Phytother Res. 2002;16(7):621-6.
http://dx.doi.org/10.1002/ptr.948
14. al-Yahya MA et al, Gastroprotective activity of ginger zingiber officinale rosc., in albino rats. Am J Chin Med. 1989;17(1-2):51-6.
http://dx.doi.org/10.1142/S0192415X89000097
15. Srivastava KC, Mustafa T, Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypotheses. 1992;39(4):342-8.
http://dx.doi.org/10.1016/0306-9877(92)90059-L