| Name: |
Thymol |
|---|
| Synonyms: |
3-p-Cymenol, alpha-Cymophenol, 3-Hydroxy p-cymene, 3-Methyl-6-isopropylphenol, Thyme camphor[1]
2-hydroxy-1-isopropyl-4-methyl benzene[2]
2-isopropyl-5-methylphenol[3]
|
|---|
| Trade name: |
preparation containing thyme
extract (Bronchipret® TP tablets)[4]
|
|---|
| Chemical name: |
5-Methyl-2-(1-methylethyl)phenol[1]
|
|---|
| Molecular Weight: |
150.22 g/mol[1]
|
|---|
| Source: |
It is one of the constituents of oil derived from Thyme(Thymus vulgaris L.)[5]
|
| Structure: |
 [2],[6]
|
| Chemical Nature: |
|
| Actions & Indications: |
Pharmcological Action-
hepatoprotective in mice[7]
Therapeutic indications:
Preclinical study-
|
| Notes: |
|
| REFERENCES |
| 1. |
Section B. Specifications of Certain flavouring Agents ; In : Compendium of Food Additive Specifications: Addendum 8 by Food and Agriculture Organization of the United Nations, Food & Agriculture Org., 2000, page no. 170.
https://books.google.co.in/books?id=0vCbGRfCG04C&pg=PA170 |
| 2. |
1. Thermochemistry by Gilbert GL et al ; In : Chemical Demonstrations: A Handbook for Teachers of Chemistry, Volume 1 by Shakhashiri BZ, Univ of Wisconsin Press, 1983, page no. 35.
https://books.google.co.in/books?id=0rx6Cjx_l-AC&pg=PA35 |
| 3. |
Chapter 13. Benzene and its derivatives ; In : Introduction to General, Organic and Biochemistry by Bettelheim FA et al, Cengage Learning, 2015, page no. 331.
https://books.google.co.in/books?id=wxadBQAAQBAJ&pg=PA331 |
| 4. |
Kohlert C et al, Systemic availability and pharmacokinetics of thymol in humans. J Clin Pharmacol. 2002;42(7):731-7.
http://dx.doi.org/10.1177/009127002401102678 |
| 5. |
Handbook of Arabian Medicinal Plants, by Ghazanfar SA, CRC Press, 1994, page no. 128.
https://books.google.co.in/books?id=8CATyYuAeuEC&pg=PA128 |
| 6. |
Archana PR et al, Thymol, a naturally occurring monocyclic dietary phenolic compound protects
Chinese hamster lung fibroblasts from radiation-induced cytotoxicity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis
2009;680(1-2):70–77.
http://dx.doi.org/10.1016/j.mrgentox.2009.09.010 |
| 7. |
Alam K et al, The protective action of thymol against carbon tetrachloride hepatotoxicity in mice. Pharmacol Res. 1999 ;40(2):159-63.
http://dx.doi.org/10.1006/phrs.1999.0472 |
