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Rosmarinus officinalis

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GENERAL FEATURES

Name: Rosmarinus officinalis
Synonyms/Scientific names: Rosmarinus officinalis L.[1],[2]
Synonyms/common names :
Rosemary[1],[3]
Polar plant, Compass weed, Compass plant[3]
Trade name:
water soluble AquaROX® 15,
oil soluble VivOX®[4]
Description: Family : Lamiaceae[3]
Extract used: Leaf:
Distilled water extract of leaves has been used for radioprotection study[5]
Phyto-constituents
(active):
Carnosic acid, cis-Rosmarinic acid, trans-Rosmarinic acid, Betulin, Oleanolic acid, Betulinic acid, Ursolic acid[6]
Rosmarinic acid, carnosol, carnosic acid, kaempferol, luteolin, genkwanin, and ladanein [7]
leaves
rosmanol[8]
α-pinene, α-phellandrene, Terpinolene, Limonene, β-phellandrene, Camphor, Borneol, Terpinen-4-ol, Terpineol, Verbenone, Carvacrol, Bornyl acetate, Caryophyllene, α-humulene, Methyl jasmonate, α--bisabolol, Benzenesulfonamide, n-butyl, Phytol, Sclareol, Ferruginol, Hinokione, Isocarnosol, Dihydronormorphinone [9]
Actions
& Indications:
Pharmcological Action-
anti-inflammatory in mice[10]
hepatoprotective in rat model[11],[12]
Therapeutic indications:
Preclinical study-
Aqueous extract showed diuretic effect in Wistar rats in vivo[13]
Notes:
REFERENCES
1. World Spice Plants: Economic Usage, Botany, Taxonomy, by Seidemann J, Springer, 2005, Page no. 320.
https://books.google.com.sg/books?id=jjkAHi2IeOkC&pg=PA320
2. Encyclopedia of Food and Color Additives, Volume 3, P-Z Index, by Burdock GA, CRC Press, 1997, Page no. 2446.
https://books.google.com.sg/books?id=NtaR9i3hYCYC&pg=PA2446
3. Chapter 84 : Rosemary; In : Medical Toxicology of Natural Substances: Foods, Fungi, Medicinal Herbs, Plants and venomous Animals by Barceloux DG, Wiley, 2012, Page no. 1409.
https://books.google.com/books?id=aTTBPedwFfAC&pg=PT1409
4. Zegura B et al, Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells. Environ Toxicol Pharmacol. 2011;32(2):296-305.
http://dx.doi.org/10.1016/j.etap.2011.06.002
5. Acharya GS, Goyal PK, Role of Rosemary leaves extract against radiation-induced hematological and biochemical alterations in mice. Nuclear Technology and Radiation Protection 2008;23(2): 72-78.
http://dx.doi.org/10.2298/NTRP0802072A
6. Razborsek MI et al, Determination of Major Phenolic Acids, Phenolic Diterpenes and Triterpenes in Rosemary (Rosmarinus officinalis L.) by Gas Chromatography and Mass Spectrometry. Acta Chim. Slov. 2007; 54: 60–67.
http://acta-arhiv.chem-soc.si/54/54-1-60.pdf
7. Bai N et al, Flavonoids and phenolic compounds from Rosmarinus officinalis. J. Agric. Food Chem. 2010; 58 (9):5363–5367.
http://dx.doi.org/10.1021/jf100332w
8. Inatani R et al, Structure of a new antioxidative phenolic diterpene isolated from Rosemary (Rosmarinus officinalis L.). Agricultural and Biological Chemistry. 1982;46(6):1661-1666.
http://dx.doi.org/10.1080/00021369.1982.10865273
9. Genena AK et al, Rosemary (Rosmarinus officinalis) – a study of the composition, antioxidant and antimicrobial activities of extracts obtained with supercritical carbon dioxide. Ciênc. Tecnol. Aliment. 2008; 28(2): 463-469.
http://dx.doi.org/10.1590/S0101-20612008000200030
10. Emami F et al, Hydroalcoholic extract of rosemary (Rosmarinus officinalis L.) and its constituent carnosol inhibit formalin-induced pain and inflammation in mice. Pakistan Journal of Biological Sciences.2013; 16: 309-316.
http://dx.doi.org/10.3923/pjbs.2013.309.316
11. Lucarini R et al, Hepatoprotective effect of Rosmarinus officinalis and rosmarinic acid on acetaminophen induced liver damage. Emir. J. Food Agric. 2014; 26(10): 878-884.
http://dx.doi.org/10.9755/ejfa.v26i10.17836
12. Amin A, Hamza AA, Hepatoprotective effects of Hibiscus, Rosmarinus and Salvia on azathioprine-induced toxicity in rats. Life Sciences 2005;77:266–278.
http://dx.doi.org/10.1016/j.lfs.2004.09.048
13. Haloui M et al, Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea. J Ethnopharmacol. 2000 ;71(3):465-72.
http://dx.doi.org/10.1016/S0378-8741(00)00184-7