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Quercetin

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: Quercetin
Synonyms: Cyanidelonon 1522; Flavin Meletin; Quercetine; Quercetol; Quertin; Quertine; Sophoretin; Xanthaurine[1-national]
Trade name: Quercetin-500 Plus capsules[2-moon]
Chemical name: 3,3',4',5,7-pentahydroxyflavone[3-arvindakshan]
3,5,7,3',4'Pentahydroxyflavone;
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one[1-national]
Molecular Weight:
Source: Many raw fruits andd vegetables are reported to be source of Quercetin.[4-ramesh]
Quercetin is a flavanol present in major quantities in onions and tea.[5-ross]
Structure: [6-jitka],[4-ramesh],[7-hosseinheimer]
Chemical Nature:
Actions
& Indications:
Pharmcological Action-
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. National Toxicology Program, Toxicology and Carcinogenesis Studies of Quercetin (CAS No. 117-39-5) in F344 Rats (Feed Studies). Natl Toxicol Program Tech Rep Ser. 1992;409:1-171.
https://www.ncbi.nlm.nih.gov/pubmed/12621521
2. Moon YJ et al, Quercetin pharmacokinetics in humans. Biopharm Drug Dispos. 2008;29(4):205-17.
http://dx.doi.org/10.1002/bdd.605
3. Aravindakshan M, Chauhan PS, Sundaram K, Studies on germinal effects of quercetin, a naturally occurring flavonoid. Mutat Res. 1985;144(2):99-106.
http://dx.doi.org/10.1016/0165-7992(85)90010-7
4. III. Common Neutraceuticals. 32. Quercetin; In : Nutraceuticals: Efficacy, Safety and Toxicity edited by Gupta RC, Academic Press, 2016, page no. 448.
https://books.google.co.in/books?id=tfJeBwAAQBAJ&pg=PA448
5. Ross JA, Kasum CM, Dietary flavanoids: bioavailability, metabolic effects, and safety. Annu. Rev. Nutr. 2002; 22:19–34.
http://dx.doi.org/10.1146/annurev.nutr.22.111401.144957
6. Křížková J et al, The effects of selected flavonoids on cytochromes P450 in rat liver and small intestine. Interdisc Toxicol. 2009; 2(3): 201–204.
http://dx.doi.org/10.2478/v10102-009-0018-y
7. Hosseinimehr SJ, Flavonoids and genomic instability induced by ionizing radiation. Drug Discovery Today 2010;15(21/22):907-918.
http://dx.doi.org/10.1016/j.drudis.2010.09.005