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Piper longum

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GENERAL FEATURES

Name: Piper longum
Synonyms/Scientific names: Piper longum Linn.[1]
Synonyms/common names :
Pippali, long pepper[1]
Trade name:
Description: Family : Piperaceae[1]
Extract used:
Phyto-constituents
(active):
coumaperine; N-5-(4-hydroxy-3-methoxyphenyl)-2E-pentenoyl piperidine; piperolactam A; 1-[1-oxo-5 (3,4-methylenedioxyphenyl) -2E,4E-pentadienyl] -pirrolidine ; 1-[1-oxo-5 (3,4-methylenedioxyphenyl) -2E-pentenyl] -pirrolidine; 1-[1-oxo-9 (3,4-methylene dioxyphenyl)-2E, 8E-nonadienyl] -pyrrolidine; (R)-(-) -turmerone; octahydro-4-hydroy-3alpha-methyl-7-methylene-alpha-(1-methylethyl)-1H-indene-1-methanol; (+) -aphanamol I ; bisdemethoxycurcumin; demethoxycurcumin[2]
1-(3',4'-methylenedioxyphenyl)-1E-tetradecene; 3-(3', 4'-methylenedioxophenyl)-propenal; piperoic acid; 3',4'-di-hydroxy-biabola-1,10-diene; eudesm-4(15)-ene-1beta, 6alpha-diol; 7-epi- eudesm-4(15)-ene-1beta, 6beta-diol; guineesine; piperine; pipericide; 2E, 4E-dienamide; (2E, 4E, 8E) -N-isobutylhenicosa-2,4,8-trienamide; piperlonguminine; methyl piperate[3]
Actions
& Indications:
Pharmcological Action-
immunomodulatory and antitumor activity in mice.[4]
analgesic in animals[5]
hepatoprotective in rats[6]
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Piper longum Linn. ; In : Ayurvedic Pharmacopoeial Plant Drugs: Expanded Therapeutics by Khare CP, CRC Press, 2015, page no. 437.
https://books.google.co.in/books?id=MSbSCgAAQBAJ&pg=PA437
2. Liu W et al, Chemical constituents from Piper longum. Zhongguo Zhong Yao Za Zhi. 2009;34(22):2891-4.
https://www.ncbi.nlm.nih.gov/pubmed/20209953
3. Liu W et al, Chemical constituents from air-dried Piper longum. Zhongguo Zhong Yao Za Zhi. 2009 ;34(9):1101-3.
https://www.ncbi.nlm.nih.gov/pubmed/19685743
4. Sunila ES, Kuttan G, Immunomodulatory and antitumor activity of Piper longum Linn. and piperine. Journal of Ethnopharmacology 2004;90(2–3):339–346.
http://dx.doi.org/10.1016/j.jep.2003.10.016
5. Vedhanayaki G, Shastri GV, Kuruvilla A, Analgesic activity of Piper longum Linn. root. Indian J Exp Biol. 2003;41(6):649-51.
http://nopr.niscair.res.in/bitstream/123456789/23337/1/IJEB%2041(6)%20649-651.pdf
6. Christina AJ et al, Inhibition of CCl4-induced liver fibrosis by Piper longum Linn.? Phytomedicine. 2006;13(3):196-8.
http://dx.doi.org/10.1016/j.phymed.2004.01.009