| Name: |
Phyllanthus amarus |
|---|
| Synonyms/Scientific names: |
Phyllanthus amarus Schumach. & Thonn.[1]
Phyllanthus niruri auct. non L.[1]
Synonyms/common names :
Black catnip, Carry me seed, gale of wind, hurricane seed[1]
Trade name:
|
|---|
| Description: |
Family : Euphorbiaceae[1]
|
| Extract used: |
|
| Phyto-constituents(active): |
ellagitannins : amariin; 1-galloyl-2,3-dehydrohexahydroxydiphenyl (DHHDP)-glucose;
repandusinic acid; geraniin; corilagin; phyllanthusiin D; flavonoids: rutin; and quercetin 3-O-glucoside.[2]
Lignans:
isolintetralin (2,3-demethoxy-seco-isolintetralin diacetate); demethylenedioxy-niranthin;
5-demethoxy-niranthin; niranthin; phyllanthin and hypophyllanthin[3]
phyllanthin, hypophyllanthin, niranthin, and nirtetralin[4]
Aerial Parts:
amariinic acid,
a novel ellagitannin; 1-O-galloyl-2,4-dehydrohexahydroxydiphenoyl-glucopyranose
elaeocarpusin, repandusinic
acid A and geraniinic acid B.[5]
|
| Actions & Indications: |
Pharmcological Action-
Hypoglycemic effect in diabetic rats[6]
hepatoprotective in rats[7]
Therapeutic indications:
It is used traditionally in treatment of gonorrhoea, diarrhoea, stomach-ache, dysentry, also used as diuretic, anti-pyretic[1]
Preclinical study-
|
| Notes: |
|
| REFERENCES |
| 1. |
Phyllanthus; In : Alphabetical Treatment of Medicinal Plants; In : Medicinal Plants, Volume 1, Plant Resources of Tropical Africa 11(1), edited by Schmelzer GH, Gurib-Fakim A, PROTA, 2008, Page no. 415.
https://books.google.com/books?id=7FJqgQ3_tnUC&pg=PA415 |
| 2. |
Londhe JS et al, Radioprotective properties of polyphenols from Phyllanthus
amarus Linn. J. Radiat. Res. 2009; 50(4): 303–309.
http://dx.doi.org/10.1269/jrr.08096 |
| 3. |
Maciel MA et al, NMR Characterization of Bioactive Lignans from Phyllanthus amarus Schum &
Thorn. Ann. Magn. Reson. 2007;6(3):76-82.
http://auremn.org/Annals/2007-vol6-num3/AMRn32007p76-82.pdf |
| 4. |
Srivastava V et al, Separation and quantification of lignans in Phyllanthus species by a simple
chiral densitometric method. J Sep Sci. 2008;31(1):47-55.
http://dx.doi.org/10.1002/jssc.200700282 |
| 5. |
Foo LY, Amariinic acid and related ellagitannins from Phyllanthus amarus. Phytochemistry 1995;39(1):217-224.
http://dx.doi.org/10.1016/0031-9422(94)00836-I |
| 6. |
Raphael KR, Sabu MC, Kuttan R, Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum &
Thonn on alloxan induced diabetes mellitus in rats and its relation with
antioxidant potential. Indian J Exp Biol. 2002 ;40(8):905-9.
http://www.ncbi.nlm.nih.gov/pubmed/12597020 |
| 7. |
Pramyothin P et al, Hepatoprotective activity of Phyllanthus amarus Schum. et. Thonn. extract in
ethanol treated rats: in vitro and in vivo studies. J Ethnopharmacol. 2007;114(2):169-73.
http://dx.doi.org/10.1016/j.jep.2007.07.037 |
