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Nardostachys jatamansi

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GENERAL FEATURES

Name: Nardostachys jatamansi
Synonyms/Scientific names: Nardostachys jatamansi D. C.[1]
Nardostachys grandiflora[2]
Synonyms/common names :
jatamansi, spikenard[3]
English name: Musk root[2]
Trade name:
Description: Family : Valerianaceae[1],[2]
Extract used: ethanolic extract[4] and aqueous suspension[5] has been used in radioprotection study.
Phyto-constituents
(active):
nardin, pyranocoumarin[6]
valeranone[7]
Wedelolactone, Quercetin and Jatamansone.[8]
jatamansic acid, jatamansone, nardostachone[1]
Actions
& Indications:
Pharmcological Action-
hepatoprotective in rats[9],[10]
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. 11. Terpenoids; In : Pharmacognosy, Forty Second Edition by Kokate CK, Purohit AP, Gokhale SP, Nirali Prakashan, 2009, 11.49
https://books.google.co.in/books?id=KwYIsLRyDp4C&pg=SA1-PA49
2. 41. Jatamansi ; In : Cultivation and Processing of Selected Medicinal Plants, NIIR Board of Consultants and Engineers, Asia Pacific Business Press Inc., 2006, page no. 369.
https://books.google.co.in/books?id=CAO3AgAAQBAJ&pg=PA369
3. Nardostachys jatamansi ; In :Herbal Treatment for Peptic Ulcer and Gastritis by By Vaidya Bhagwan D, B. Jain Publishers, 2001, page no. 76.
https://books.google.co.in/books?id=VP_dP3xocmYC&pg=PA76
4. Deepa B, Suchetha K, Rao S, Antidepressant activity of Nardostachys jatamansi in electron beam irradiated mice. International Journal of Research in Ayurveda and Pharmacy 2013;4(1):101-103.
http://dx.doi.org/10.7897/2277-4343.04135
5. Gowda DKM et al, The efficacy of Nardostachys jatamansi against the radiation induced haematological damage in rats. Journal of Clinical and Diagnostic Research 2013 ;7(6):982-986.
http://dx.doi.org/10.7860/JCDR/2013/5475.3078
6. Chatterjee A et al, Studies on the chemical constituents of Nardostachys jatamansi DC (Valerianaceae). Indian Journal of Chemistry 2005;44B:430-433.
http://nopr.niscair.res.in/bitstream/123456789/8953/1/IJCB%2044B(2)%20430-433.pdf
7. Rücker G et al, Isolation and pharmacodynamic activity of the sesquiterpene valeranone from Nardostachys jatamansi DC. Arzneimittelforschung. 1978;28(1):7-13.
https://www.ncbi.nlm.nih.gov/pubmed/580202
8. Thorat RM et al, Development of HPTLC method for estimation of Wedelolactone, Quercetin and Jatamansone in Polyherbal Formulation. International Journal of ChemTech Research 2009;1(4):1079-1086.
http://sphinxsai.com/ctvol4/ct_pdf_vol_4/ct=47%20(1079-1086)(1).pdf
9. Ali S et al, Nardostachys jatamansi protects against liver damage induced by thioacetamide in rats. J Ethnopharmacol. 2000 ;71(3):359-63.
http://dx.doi.org/10.1016/S0378-8741(99)00153-1
10. Aleem MA, Ibrahim M, Hepato protective activity of Hydroalcoholic extract of Nardostachys jatamansi in Carbon tetrachloride induced hepatotoxicity in rats. International Journal of Pharmaceutical Applications 2014;5(2):8-13.
http://bipublication.com/files/IJPA-V5I22014-01.pdf