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Bioinformatics Database on
"Radiosensitisers and Radioprotectors"

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MLN4924

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: MLN4924
Synonyms: Pevonedistat, TAK924[1]
Trade name:
Chemical name:
Molecular Weight:
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Structure: [2]
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& Indications:
Pharmcological Action-
Therapeutic indications:
Preclinical study-
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REFERENCES
1. Sarantopoulos J et al, Phase I study of the investigational NEDD8-activating enzyme inhibitor Pevonedistat (TAK-924/MLN4924) in patients with advanced solid tumors. Clin Cancer Res. 2016 ;22(4):847-57.
http://dx.doi.org/10.1158/1078-0432.CCR-15-1338
2. Wang X et al, Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells. Oncotarget. 2016; 7(25): 38380–38391.
http://dx.doi.org/10.18632/oncotarget.9526