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Hypericum perforatum

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GENERAL FEATURES

Name: Hypericum perforatum
Synonyms/Scientific names: Hypericum perforatum Linn.[1]
St, John's Wort, Amber, demon Chaser, Fuga Daemonum, goatweed, Hardhay, Klamath weed, Rosin Rose[2]
Description: Family : Hypericaceae[1],[2]
Extract used:
Phyto-constituents
(active):
I3,II8-Biapigenin.[3]
hypericin and hyperforin[4]
Actions
& Indications:
Pharmcological Action-
Therapeutic indications:
Extracts of hypericum are found to be more effective than placebo for the treatment of mild to moderately severe depressive disorders in patinets in clinical setting.[5]
Preclinical study-
Notes:
REFERENCES
1. St. John's Wort; In : Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second edition, by Mckenna DJ et al, Routledge, 2012, page no. 923.
https://books.google.co.in/books?id=soksBgAAQBAJ&pg=PA923
2. St. John's Wort; In : Neurological Drug Reactions and Interactions by Litt JZ et al, CRC Press, 2005, page no. 160.
https://books.google.co.in/books?id=PVAVJeLGtooC&pg=PA160
3. Berghöfer R , Hölzl J, Biflavonoids in Hypericum perforatum 1; Part 1. Isolation of I3, II8-Biapigenin. Planta Med. 1987 ;53(2):216-7.
https://dx.doi.org/10.1055/s-2006-962676
4. Vacek J, Klejdus B, Kubán V, Hypericin and hyperforin: bioactive components of St. John's Wort (Hypericum perforatum). Their isolation, analysis and study of physiological effect. Ceska Slov Farm. 2007 ;56(2):62-6.
https://www.ncbi.nlm.nih.gov/pubmed/17619301
5. Linde K et al, St John's wort for depression--an overview and meta-analysis of randomised clinical trials. BMJ 1996;313(7052):253-8.
http://dx.doi.org/10.1136/bmj.313.7052.253