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Bioinformatics Database on
"Radiosensitisers and Radioprotectors"

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Gimeracil

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: Gimeracil
Synonyms:
Trade name:
Chemical name: 5-chloro-2,4-dihydroxypyridine[1]
Molecular Weight:
Source: Gimeracil is a component of an oral fluoropyrimidine derivative S-1.[2]
Structure: [1]
Chemical Nature:
Actions
& Indications:
Pharmcological Action-
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Matsumoto Y et al, Chapter:23 Radiosensitization strategies through modification of DNA double-strand break repair; In: New Research Directions in DNA Repair, Prof. Clark Chen (Ed.), InTech, 2013, 639-661.
http://dx.doi.org/10.5772/54684
2. Sakata K et al, Mechanisms of radiosensitization by Gimeracil, inhibitor of dihydropyrimidine dehydrogenase. Int J Radiat Oncol Biol Phy 2011;81(2, Supplement):S713.
http://dx.doi.org/10.1016/j.ijrobp.2011.06.1266