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Genistein

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GENERAL FEATURES

Name: Genistein
Synonyms:
Trade name:
Chemical name: 4',5,7-trihydroxyisoflavone[1]
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one[2]
Molecular Weight: 270.23 g/mol[3]
Source: Genistein is a naturally occurring isoflavone found in soybeans, is a phytoestrogen.[4]
Structure: [3],[5]
Chemical Nature:
Actions
& Indications:
Pharmcological Action-
anti-inflammatory in mice[6]
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Canyilmaz E et al, Comparison of the effects of melatonin and genistein on radiation-induced nephrotoxicity: Results of an experimental study. Biomedical Reports 2016;4:45-50.
http://dx.doi.org/10.3892/br.2015.547
2. Encyclopedia of Cancer, 3rd edition, edited by Schwab M, Springer Science & Business Media, 2011, page no. 784.
https://books.google.co.in/books?id=yMFN5dvgNscC&pg=PA784
3. Technical Report on the Toxicology and Carcinogenesis Study of Genistein (CAS No. 446-72-0) in Sprague-Dawley Rats (Feed Study) by edited Casciano DA, DIANE Publishing, 2008, page no. 19.
https://books.google.co.in/books?id=LqmdD0hAu0AC&pg=PA19
4. Landauer MR et al, Protection from lethal irradiation by Genistein; In : Abstracts for the 21st Annual Meeting of the American College of Toxicology November 12–15, 2000 San Diego, California, USA.
http://dx.doi.org/10.1080/109158100750058785
5. Landauer MR et al, Prevention of gamma radiation-induced mortality in mice by the isoflavone genistein, published by Defense Technical Information Center, 2005, pages 12.
http://www.dtic.mil/dtic/tr/fulltext/u2/a438759.pdf
6. Verdrengh M et al, Genistein as an anti-inflammatory agent. Inflamm Res. 2003 ;52(8):341-6.
http://dx.doi.org/10.1007/s0001100311828