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Epoetin alpha

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: Epoetin alpha
Synonyms:
Trade name: Epogen®, Procrit®[1], Ortho Biotech Products, L.P.; Bridgewater, NJ[2]
Neorecormon, Roche[3]
Chemical name:
Molecular Weight: It has a molecular weight of 30,400 Da.[4]
Source:
Structure:
Chemical Nature: It has three asparagine-linked carbohydrate chains and O-linked glycosylation sites.[5]
Actions
& Indications:
Pharmcological Action-
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Epogen/Procrit; In : Directory of Approved Biopharmaceutical Products by Spada S, Walsh G, CRC Press, 2004, page no. 39.
https://books.google.com.sg/books?id=CZaCXXVvirEC&pg=PA39
2. Shasha D, George MJ, Harrison LB, Once-weekly dosing of epoetin-alpha increases hemoglobin and improves quality of life in anemic cancer patients receiving radiation therapy either concomitantly or sequentially with chemotherapy. Cancer. 2003 ;98(5):1072-9.
http://dx.doi.org/10.1002/cncr.11616
3. Nigro CL et al, Impact of erythropoietin (EPO) on irradiation effect on the EPO receptor positive head and neck cancer. Can Res 2008; 68(9 Supplement).
http://cancerres.aacrjournals.org/content/68/9_Supplement/5771
4. 15. Anabolic doping agent by von Deutsch DA et al; In : Handbook of Drug Interactions: A Clinical and Forensic Guide, 2nd edition, edited by Mozayani A, Raymon L, Springer Science & Business Media, 2011, page no. 726.
https://books.google.co.in/books?id=NhBJ6kg_uP0C&pg=PA726
5. Egrie JC et al, Characterization and biological effects of recombinant human erythropoietin. Immunobiol. 1986;172(3-5):213-224.
http://dx.doi.org/10.1016/S0171-2985(86)80101-2