Welcome to University of Mumbai, Department of Biophysics

Bioinformatics Database on
"Radiosensitisers and Radioprotectors"

Alphabetical Search   >  A   >  Amaranthus paniculatus                                                                                                                                                                 Top

Amaranthus paniculatus

Go To:

General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
Radiobiological Aspects                  Biological Models                  Biological Target                  Toxicity                 


Name: Amaranthus paniculatus
Synonyms Botanical Name: Amaranthus paniculatus (Linn.)[18],[14], [13]
Synonyms/common names :Rajgira(Ramdana)[1], Halon[2],Amaranth in English[3],panicle amaranth, redshaank, wild amaranth[13]
Amaranthus cruentus L.[14],[13],[19],[20]
Trade name:
Description: Family : amaranthaceae[14], [13],[2]
It is an erect, stout, branched, unarmed, annual herb[14],[2]
Amaranth grain is used largely for feeding children and the elderly[4]
Chemical Nature:
Extract used: metanolic extract for a radiprotection experiment[15]
ethanolic extract[5]
ethanolic extract[6]
methanolic extract[16]
Aqueous extract[17]
Aerial parts:
Hydroacetonic, methanolic, and aqueous extracts[7]
root bark:
Amaranth grain is a good source of protein and vitamins[4]
Carotenoids, vitamin C, folic acid,lysine, methionine, amino acids, β-carotene, vitamin E, vitamin A[2],[6]
polyphenols, tannins, flavonoids, steroids, terpenoids, saponins, and betalains.[6]
phenolics, some of the essential amino acids[8]
gallic acid[9]
anthocyanins, flavanoids[9]
Protocatechuic acid, gallic and sinapic acid, p-Hydroxybenzoic acid, caffeic acid[5]
Aerial parts:
Tannins, flavonoids, and flavonols, gallic acid, rutin, betacyanin, Steroids and triterpenes Iridoids, Cardenolids, Carotenoids, Sapononins[7]
& Indications:
Pharmcological Action-
antianemic activity in rats[6]
hepatoprotective in rats[9]
Therapeutic indications:
Preclinical study-
Amaranth products showed binding activity for secondary bile acids toxic to the intestinal mucus.[10]
A. cruentus is suggested to have hypocholesterolemic effect[11]
Notes: Preparation of Amaranthus baby formula that matches pre-existing soy-oat infant formulas has been reported[12]
1. Kasera R et al, First case report of anaphylaxis caused by Rajgira seed flour (Amaranthus paniculatus) from India: a clinico-immunologic evaluation. Asian Pac J Allergy Immunol. 2013;31(1):79-83.
2. Kumar A, Revathi K, Mohanalakshmi S, A review on edible herbs as haematinic. International Journal of Pharmacy. 2012; 2(2):44-53.
3. Sreelatha S, Dinesh E, Uma C, Antioxidant properties of Rajgira (Amaranthus paniculatus) leaves and potential synergy in chemoprevention. Asian Pacific J Cancer Prev. 2012;13:2775-2780.
4. Mburu MW et al, Properties of a complementary food based on Amaranth Grain (Amaranthus cruentus) grown in Kenya. J. Agric. Food. Tech. 2011;1(9)153-178.
5. Klimczak I, Malecka M, Pacholek B, Antioxidant activity of ethanolic extracts of amaranth seeds. Nahrung/Food 2001;46(3)184 - 186.
6. Pandey S et al, Hematopoietic effect of Amaranthus cruentus extract on Phenylhydrazine-induced toxicity in rats. Journal of Dietary Supplements. Early Online. 2016;1–9.
7. Nana FW et al, Phytochemical composition, antioxidant and xanthine oxidase inhibitory activities of Amaranthus cruentus L. and Amaranthus hybridus L. extracts. Pharmaceuticals 2012;5:613-628.
8. Cheeke PR, Carlsson R, Kohler GO, Nutritive value of leaf protein concentrates prepared from Amaranthus species. Can. J. Anim. Sci. 1981;6l(1): 199-204.
9. Escudero NL et al, Antioxidant activity and phenolic content of flour and protein concentrate of Amaranthus cruentus seeds. Journal of Food Biochemistry 2011; 35:1327–1341.
10. Tiengo A, Motta EM, Netto FM, Chemical composition and bile acid binding activity of products obtained from amaranth (Amaranthus cruentus) seeds. Plant Foods Hum Nutr. 2011;66(4):370-5.
11. Soares RAM et al, Major peptides from Amaranth (Amaranthus cruentus) protein inhibit HMG-CoA reductase activity. Int. J. Mol. Sci. 2015;16:4150-4160.
12. Valle FRD et al, Chemical and nutritional evaluation of two amaranth (Amaranthus cruentus)- based infant formulas. Plant Foods for Human Nutrition. 1993;43(2):145-156.
13. International Poisonous Plants Checklist: An Evidence-Based Reference by Wagstaff JD, CRC Press, 2008, page no 20
14. Alphabetical Treatment of Vegetables; In : Vegetables, Pplant Resources of Tropical Africa 2, edited by Grubben GJH, Denton OA, backhuys Publishers, 2004, page no. 67.
15. Bhatia AL, Jain M, Amaranthus paniculatus (Linn.) improves learning after radiation stress. Journal of Ethnopharmacology 2003;85(1): 73–79.
16. Jain M, Sisodia R, Bhatia AL, Studies of methanolic extract of Amaranthus paniculatus L. on mice liver against gamma radiation. 11th International Congress of the International Radiation Protection Association, 23-28 May 2004, Madrid, Spain.
17. Krishna A, Kumar A, Evaluation of radioprotective effects of Rajgira(Amaranthus paniculatus) extract in Swiss albino mice. J. Radiat. Res.2005; 46(2): 233–239.
18. Manikandan PN, Ethno- medico - botanical studies of Badaga population Iin the Nilgiri district of Tamilnadu, South India. Anc Sci Life. 2008;27(3):50-9.
19. World Economic Plants: A Standard Reference, Second Edition By Wiersema JH, León B, CRC Press, 2016, page no. 44.
20. Multilingual Dictionary of Agronomic Plants edited by Rehm G, Springer Science & Business Media, 2012, page no. 14.