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Allium sativum

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: Allium sativum
Synonyms/Scientific names: Allium sativum L. [1]
Porrum sativum (L.) Rchb. [2]
Synonyms/common names :
common garlic, garlic[1],[2]
Trade name:
Description: Family : Amaryllidaceae[1]
Extract used: Aqueous and ethanolic boiled extract has been used for radioprotection study[3],[4]
Phyto-constituents
(active):
Alliin and allicin[5]
essential oil :
saturated and unsaturated fatty acids, Diallyl sulphide, Allyl mehyl disulfide, Allyl methyl sulphide, Dimethyl trisulphide, Diallyl disulfide, Allyl methyl trisulphide, 3-vinyl-1,2-dithiin, 2-vinyl-1,3-dithiin [6]
diallyl trisulfide, diallyl disulfide, and methyl allyl trisulfide[7]
Actions
& Indications:
Pharmcological Action-
antidiabetic in rats[8]
antiinflammatory and immunomodulator[9]
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Allium sativum ; In : Edible Medicinal and Non Medicinal Plants: Volume 9, Modified Stems, Roots, Bulbs, by Lim TK, Springer, 2014, Page no. 210.
https://books.google.com/books?id=t22vBQAAQBAJ&pg=PA210
2. Allium sativum ; In : World Spice Plants: Economic Usage, Botany, Taxonomy, by Seidemann J, Springer Science & Business Media, 2005, Page no.24.
https://books.google.com/books?id=fhN0VK2608QC&pg=PA24
3. Rao SN et al, Radioprotective properties of Allium sativum (Garlic) extract on cultured human lymphocytes against electron beam radiation. International Journal of Pharmaceutical Sciences and Drug Research 2015; 7(2): 151-156.
http://www.ijpsdr.com/pdf/vol7-issue2/4.pdf
4. Batcioglu K et al, Investigation of in vivo radioprotective and in vitro antioxidant and antimicrobial activity of garlic (Allium Sativum). European Review for Medical and Pharmacological Sciences. 2012; 16(Suppl 3): 47-57.
http://www.europeanreview.org/article/1250
5. Ghani MJ, Determination of Alliin and Allicin in different types Garlic using high performance liquid chromatography. J. of university of anbar for pure science 2010; 4(2) :
http://www.iasj.net/iasj?func=fulltext&aId=15391
6. Chekki RZ et al, Chemical composition, antibacterial and antioxidant activities of Tunisian garlic (Allium sativum) essential oil and ethanol extract. Mediterr.J.Chem. 2014; 3(4): 947-956
http://dx.doi.org/10.13171/mjc.3.4.2014.09.07.11
7. Mallet ACT et al, Chemical characterization of the Allium sativum and Origanum vulgare essential oils and their inhibition effect on the growth of some food pathogens. Rev. Bras. Pl. Med., Campinas 2014;16(4):804-811.
http://www.scielo.br/pdf/rbpm/v16n4/a04v16n4.pdf
8. Eidi A, Eidi M, Esmaeili E, Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine. 2006 ;13(9-10): 624-9.
http://dx.doi.org/10.1016/j.phymed.2005.09.010
9. Schäfer G, Kaschula CH, The immunomodulation and antiinflammatory effects of garlic organosulfur compounds in cancer chemoprevention. Anticancer Agents Med Chem. 2014 ;14(2):233-40.
http://dx.doi.org/10.2174/18715206113136660370