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Ageratum conyzoides

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Name: Ageratum conyzoides
Synonyms/Scientific names: Ageratum conyzoides (L.) L.[1]
Synonyms/common names :
Ageratum album Willd. ex. Steud.[2]
Ageratum, Appa grass, Billy-goat weed, Chick weed[1],[2]
Trade name:
Description: Family : Asteraceae[1],[2]
Extract used: 95% ethanolic extract of whole plant has been used in radioprotection study[3]
Alkaloids, flavonoids, saponins, tannins, cardiac glycosides and anthraquinones[4]
5,6,7,8,3', 4', 5'-heptamethoxyflavone; 5,6,7,8,3'-pentamethoxy-4', 5'-methylenedioxyflavone; and coumarin[5]
5,6,8,3',4',5'-hexamethoxyflavone and 8-hydroxy-5,6,7,3',4',5'-hexamethoxyflavone[6]
2-(2'-methylethyl)-5,6-dimethoxybenzofuran; 2-(1'-oxo-2'-methylpropyl)-2-methyl-6,7-dimethoxy-chromene; 3-(2'-methylpropyl)-2-methyl-6,8-dimethoxy-chrom-4-one and 2-(2'-methylprop-2'-enyl)-2-methyl-6,7-dimethoxy-chroman-4-one [7]
& Indications:
Pharmcological Action-
antinociceptive and antioxidant activity[8]
hepatoprotective in rats[9]
hypoglycaemic in rats[10]
analgesic and anti-inflammatory activity in rats[11]
Therapeutic indications:
Preclinical study-
1. Ageratum conyzoides ; In : Edible Medicinal And Non-Medicinal Plants: Volume 7, Flowers, by Lim TK, Springer Science & Business Media, 2013, page no. 175.
2. Plants with Anti-Diabetes Mellitus Properties by Subramoniam A, CRC Press, 2016, page no. 42.
3. Jagetia GC et al, Evaluation of the radioprotective effect of Ageratum conyzoides Linn. extract in mice exposed to different doses of gamma radiation. J Pharm Pharmacol. 2003;55(8):1151-8.
4. Agbafor KN, Engwa AG, Obiudu IK, Analysis of chemical composition of leaves and roots of Ageratum conyzoides. Int J Curr Res Aca Rev 2015;3(11):60-65.
5. Moreira MD et al, Compounds from Ageratum conyzoides: isolation, structural elucidation and insecticidal activity. Pest Manag Sci. 2007 ;63(6):615-21.
6. González AG et al, Methoxyflavones from Ageratum conyzoides. Phytochemistry 1991;30(4);1269–1271.
7. Pari K et al, Benzofuran and other constituents of the essential oil of Ageratum conyzoides. Phytochemistry 1998,;49(5):1385–1388.
8. Hossain H et al, Antinociceptive and antioxidant potential of the crude ethanol extract of the leaves of Ageratum conyzoides grown in Bangladesh.Pharm Biol. 2013;51(7):893-8.
9. Verma PK et al, Hepatoprotective effects of Ageratum conyzoides L. on biochemical indices induced by Acetaminophen toxicity in Wistar rats. Journal of Applied Pharmaceutical Science 2013;3 (4 Suppl 1):S23-S27.
10. Nyunaï N et al, Hypoglycaemic and antihyperglycaemic activity of Ageratum conyzoides L. in rats. Afr J Tradit Complement Altern Med. 2009 ;6(2):123-30.
11. Magalhães JFG et al, Analgesic and anti-inflammatory activities of Ageratum conyzoides in rats. Phytotherapy Research 1997;11(3):183-188.