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Ageratum conyzoides

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
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GENERAL FEATURES

Name: Ageratum conyzoides
Synonyms/Scientific names: Ageratum conyzoides (L.) L.[1]
Synonyms/common names :
Ageratum album Willd. ex. Steud.[2]
Ageratum, Appa grass, Billy-goat weed, Chick weed[1],[2]
Trade name:
Description: Family : Asteraceae[1],[2]
Extract used: 95% ethanolic extract of whole plant has been used in radioprotection study[3]
Phyto-constituents
(active):
Alkaloids, flavonoids, saponins, tannins, cardiac glycosides and anthraquinones[4]
5,6,7,8,3', 4', 5'-heptamethoxyflavone; 5,6,7,8,3'-pentamethoxy-4', 5'-methylenedioxyflavone; and coumarin[5]
5,6,8,3',4',5'-hexamethoxyflavone and 8-hydroxy-5,6,7,3',4',5'-hexamethoxyflavone[6]
2-(2'-methylethyl)-5,6-dimethoxybenzofuran; 2-(1'-oxo-2'-methylpropyl)-2-methyl-6,7-dimethoxy-chromene; 3-(2'-methylpropyl)-2-methyl-6,8-dimethoxy-chrom-4-one and 2-(2'-methylprop-2'-enyl)-2-methyl-6,7-dimethoxy-chroman-4-one [7]
Actions
& Indications:
Pharmcological Action-
antinociceptive and antioxidant activity[8]
hepatoprotective in rats[9]
hypoglycaemic in rats[10]
analgesic and anti-inflammatory activity in rats[11]
Therapeutic indications:
Preclinical study-
Notes:
REFERENCES
1. Ageratum conyzoides ; In : Edible Medicinal And Non-Medicinal Plants: Volume 7, Flowers, by Lim TK, Springer Science & Business Media, 2013, page no. 175.
https://books.google.co.in/books?id=Xj1dAwAAQBAJ&pg=PA175
2. Plants with Anti-Diabetes Mellitus Properties by Subramoniam A, CRC Press, 2016, page no. 42.
https://books.google.co.in/books?id=nQnYCwAAQBAJ&pg=PA42
3. Jagetia GC et al, Evaluation of the radioprotective effect of Ageratum conyzoides Linn. extract in mice exposed to different doses of gamma radiation. J Pharm Pharmacol. 2003;55(8):1151-8.
http://dx.doi.org/10.1211/0022357021576
4. Agbafor KN, Engwa AG, Obiudu IK, Analysis of chemical composition of leaves and roots of Ageratum conyzoides. Int J Curr Res Aca Rev 2015;3(11):60-65.
http://www.ijcrar.com/vol-3-11/K.%20N.%20Agbafor,%20et%20al.pdf
5. Moreira MD et al, Compounds from Ageratum conyzoides: isolation, structural elucidation and insecticidal activity. Pest Manag Sci. 2007 ;63(6):615-21.
http://dx.doi.org/10.1002/ps.1376
6. González AG et al, Methoxyflavones from Ageratum conyzoides. Phytochemistry 1991;30(4);1269–1271.
http://dx.doi.org/10.1016/S0031-9422(00)95215-4
7. Pari K et al, Benzofuran and other constituents of the essential oil of Ageratum conyzoides. Phytochemistry 1998,;49(5):1385–1388.
http://dx.doi.org/10.1016/S0031-9422(97)00803-0
8. Hossain H et al, Antinociceptive and antioxidant potential of the crude ethanol extract of the leaves of Ageratum conyzoides grown in Bangladesh.Pharm Biol. 2013;51(7):893-8.
http://dx.doi.org/10.3109/13880209.2013.770535
9. Verma PK et al, Hepatoprotective effects of Ageratum conyzoides L. on biochemical indices induced by Acetaminophen toxicity in Wistar rats. Journal of Applied Pharmaceutical Science 2013;3 (4 Suppl 1):S23-S27.
http://dx.doi.org/10.7324/JAPS.2013.34.S4
10. Nyunaï N et al, Hypoglycaemic and antihyperglycaemic activity of Ageratum conyzoides L. in rats. Afr J Tradit Complement Altern Med. 2009 ;6(2):123-30.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816573/
11. Magalhães JFG et al, Analgesic and anti-inflammatory activities of Ageratum conyzoides in rats. Phytotherapy Research 1997;11(3):183-188.
http://dx.doi.org/10.1002/(SICI)1099-1573(199705)11:3<183::AID-PTR63>3.0.CO;2-8