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Bioinformatics Database on
"Radiosensitisers and Radioprotectors"

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Rubia cordifolia

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General Features                  Clinical Study                  Chemical Intervention                 Pharmacological Aspects                 
Radiobiological Aspects                  Biological Models                  Biological Target                  Toxicity                 


CHEMICAL INTERVENTION

Effective dose
(experimental):
Mode and form of
administration:
In the form of extract[1], [2]
orally[1]
IP[2]
Time of
administration:
before irradiation[1], [2]
Side Effects:
Combined action
with other drugs
/therapies:
Root extract chelates iron by directly interacting with it[3]
Precautions &
Contraindications:
REFERENCES
1. Chapter 5 : Radioprotective, nephoprotective and anti-inflammatory activities of the plant Rubia cordifolia Linn. ; In : Modification of cellular radiosensitivity by phytoceuticals and herbal extracts: Mechanisms and relevance, a thesis by Joy J, Guide : Nair CKK, submitted to Mahatma Gandhi University, Amala Cancer Research Center, India, 2014.
http://shodhganga.inflibnet.ac.in/handle/10603/25801
2. Tripathi YB, Singh AV, Role of Rubia cordifolia Linn. in radiation protection. Indian Journal of Experimental Biology 2007; 45(7):620-625.
http://nopr.niscair.res.in/bitstream/123456789/5335/1/IJEB%2045(7)%20620-625.pdf
3. Tripathi YB, Sharma M, The interaction of Rubia cordifolia with iron redox status: a mechanistic aspect in free radical reactions. Phytomedicine. 1999 ;6(1):51-7.
http://dx.doi.org/10.1016/S0944-7113(99)80035-X